5/30/2023 0 Comments Silk microscopic view![]() Compared to normal skin, HS has a thicker dermis with denser collagen fibers. Topical drug application has the advantages of high specificity, convenience and few side effects but is less effective. Intralesional injections are often accompanied by adverse effects and fail to maintain a long-lasting high local concentration at the injection site. Surgical incisions are invasive procedures that are likely to result in new scars. However, researchers are still searching for more effective and convenient HS treatment. HS treatment includes excision, radiation therapy and the intralesional injection of steroids, 5-fluorouracil or botulinum toxin A. HSs cause organ dysfunction and motor incapacity, imposing a substantial financial burden on patients worldwide. Abnormal wound healing usually results in hypertrophic scars (HSs) or even keloids.
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